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12

Compounds

Cat No. Product Name Synonyms Targets
T18143 M-PEG12-OH Dodecaethylene Glycol Monomethyl Ether Others , PROTAC Linker
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of ant...
T16658 Boc-NH-PEG4 PROTAC Linker 12 Others
Boc-NH-PEG4, also known as PROTAC Linker 12, is a PEG-based linker compound utilized for the synthesis of PROTACs[1].
T15839 M-PEG12-amine Others
m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12 unit PEG ADC linker employed in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2].
T18675 (S,R,S)-AHPC-PEG2-NH2 dihydrochloride VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12 Others , Ligand for E3 Ligase
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1].
T14226 Amino-PEG11-amine Others , PROTAC Linker
Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent es...
T15121 Diethyl 12-bromododecylphosphonate Others
Diethyl 12-bromododecylphosphonate is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1].
T17892 CIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-Linker Conjugates 38 Others
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creatin...
T15931 M-PEG8-(CH2)12-phosphonic acid ethyl ester Others
m-PEG8-(CH2)12-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based PROTAC linker, suitable for the synthesis of PROTAC compounds[1].
T71906 Boc-12-Ado-OH
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary ...
T69771 MS-177
MS177, a potent and rapid EZH2 degrader, functions as a PROTAC comprised of a CRBN ligand, linker, and a powerful enzymatic EZH2 inhibitor C24 (C24 IC50: 12 nM). It successfully targets and depletes both canonical EZH2–P...
T71967 Fmoc-12-aminododecanoic acid
Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected un...
T79820 SMD-3040 Epigenetic Reader Domain
SMD-3040 is a potent and selective SMARCA2 PROTAC degrader (DC50: 12 nM), which consists of an SMARCA2/4 ligand, a linker, and a VHL ligand. It exhibits excellent degradation selectivity for the SMARCA2 protein over the ...
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