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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18143 | M-PEG12-OH | Dodecaethylene Glycol Monomethyl Ether | Others , PROTAC Linker |
m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of ant... | |||
T16658 | Boc-NH-PEG4 | PROTAC Linker 12 | Others |
Boc-NH-PEG4, also known as PROTAC Linker 12, is a PEG-based linker compound utilized for the synthesis of PROTACs[1]. | |||
T15839 | M-PEG12-amine | Others | |
m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12 unit PEG ADC linker employed in the synthesis of PROTACs[1] and antibody-drug conjugates (ADCs)[2]. | |||
T18675 | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride | VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12 | Others , Ligand for E3 Ligase |
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1]. | |||
T14226 | Amino-PEG11-amine | Others , PROTAC Linker | |
Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent es... | |||
T15121 | Diethyl 12-bromododecylphosphonate | Others | |
Diethyl 12-bromododecylphosphonate is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1]. | |||
T17892 | CIAP1 Ligand-Linker Conjugates 12 | E3 ligase Ligand-Linker Conjugates 38 | Others |
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creatin... | |||
T15931 | M-PEG8-(CH2)12-phosphonic acid ethyl ester | Others | |
m-PEG8-(CH2)12-phosphonic acid ethyl ester is a polyethylene glycol (PEG)-based PROTAC linker, suitable for the synthesis of PROTAC compounds[1]. | |||
T71906 | Boc-12-Ado-OH | ||
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary ... | |||
T69771 | MS-177 | ||
MS177, a potent and rapid EZH2 degrader, functions as a PROTAC comprised of a CRBN ligand, linker, and a powerful enzymatic EZH2 inhibitor C24 (C24 IC50: 12 nM). It successfully targets and depletes both canonical EZH2–P... | |||
T71967 | Fmoc-12-aminododecanoic acid | ||
Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected un... | |||
T79820 | SMD-3040 | Epigenetic Reader Domain | |
SMD-3040 is a potent and selective SMARCA2 PROTAC degrader (DC50: 12 nM), which consists of an SMARCA2/4 ligand, a linker, and a VHL ligand. It exhibits excellent degradation selectivity for the SMARCA2 protein over the ... |